BDBM50353791 CHEMBL1829256

SMILES: CCC(N(CCCN)C(=O)c1ccc(C)cc1)c1nc2ccsc2c(=O)n1Cc1cc(C)on1

InChI Key: InChIKey=GUXSBUIOWRGKPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50353791 (CHEMBL1829256) Show SMILES CCC(N(CCCN)C(=O)c1ccc(C)cc1)c1nc2ccsc2c(=O)n1Cc1cc(C)on1 Show InChI InChI=1S/C25H29N5O3S/c1-4-21(29(12-5-11-26)24(31)18-8-6-16(2)7-9-18)23-27-20-10-13-34-22(20)25(32)30(23)15-19-14-17(3)33-28-19/h6-10,13-14,21H,4-5,11-12,15,26H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assay				J Med Chem 54: 6734-50 (2011) Article DOI: 10.1021/jm200629m BindingDB Entry DOI: 10.7270/Q2ZC838Z
					More data for this Ligand-Target Pair