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SMILES: CCC(N(CCCN)C(=O)c1ccc(cc1)C(C)C)c1nc2ccsc2c(=O)n1Cc1ccccc1

InChI Key: InChIKey=OSFWTSQMFSKNRE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353793   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50353793
PNG
(CHEMBL1829408)
Show SMILES CCC(N(CCCN)C(=O)c1ccc(cc1)C(C)C)c1nc2ccsc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C29H34N4O2S/c1-4-25(32(17-8-16-30)28(34)23-13-11-22(12-14-23)20(2)3)27-31-24-15-18-36-26(24)29(35)33(27)19-21-9-6-5-7-10-21/h5-7,9-15,18,20,25H,4,8,16-17,19,30H2,1-3H3
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Article
PubMed
n/an/a 940n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assay

J Med Chem 54: 6734-50 (2011)


Article DOI: 10.1021/jm200629m
BindingDB Entry DOI: 10.7270/Q2ZC838Z
More data for this
Ligand-Target Pair