BDBM50355554 CHEMBL1910616

SMILES: NC(=N)N\N=C\c1c(nc2sc3ccccc3n12)-c1cc(Cl)sc1Cl

InChI Key: InChIKey=YYPZEEYWQBKWHA-CGOBSMCZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50355554 (CHEMBL1910616) Show SMILES NC(=N)N\N=C\c1c(nc2sc3ccccc3n12)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C15H10Cl2N6S2/c16-11-5-7(13(17)25-11)12-9(6-20-22-14(18)19)23-8-3-1-2-4-10(8)24-15(23)21-12/h1-6H,(H4,18,19,22)/b20-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK1 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50355554 (CHEMBL1910616) Show SMILES NC(=N)N\N=C\c1c(nc2sc3ccccc3n12)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C15H10Cl2N6S2/c16-11-5-7(13(17)25-11)12-9(6-20-22-14(18)19)23-8-3-1-2-4-10(8)24-15(23)21-12/h1-6H,(H4,18,19,22)/b20-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355554 (CHEMBL1910616) Show SMILES NC(=N)N\N=C\c1c(nc2sc3ccccc3n12)-c1cc(Cl)sc1Cl Show InChI InChI=1S/C15H10Cl2N6S2/c16-11-5-7(13(17)25-11)12-9(6-20-22-14(18)19)23-8-3-1-2-4-10(8)24-15(23)21-12/h1-6H,(H4,18,19,22)/b20-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair