BDBM50355606 CHEMBL1910760

SMILES: Cc1sc2nc(c(\C=N\NC(N)=N)n2c1C)-c1cc(c(Cl)cc1Cl)[N+]([O-])=O

InChI Key: InChIKey=LISYIVBPIXBFSA-DENHBWNVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50355606 (CHEMBL1910760) Show SMILES Cc1sc2nc(c(\C=N\NC(N)=N)n2c1C)-c1cc(c(Cl)cc1Cl)[N+]([O-])=O Show InChI InChI=1S/C15H13Cl2N7O2S/c1-6-7(2)27-15-21-13(12(23(6)15)5-20-22-14(18)19)8-3-11(24(25)26)10(17)4-9(8)16/h3-5H,1-2H3,(H4,18,19,22)/b20-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50355606 (CHEMBL1910760) Show SMILES Cc1sc2nc(c(\C=N\NC(N)=N)n2c1C)-c1cc(c(Cl)cc1Cl)[N+]([O-])=O Show InChI InChI=1S/C15H13Cl2N7O2S/c1-6-7(2)27-15-21-13(12(23(6)15)5-20-22-14(18)19)8-3-11(24(25)26)10(17)4-9(8)16/h3-5H,1-2H3,(H4,18,19,22)/b20-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of RSK2 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
					More data for this Ligand-Target Pair