BDBM50355805 CHEMBL1911750

SMILES: C[C@@H]1COc2ccc(OC(F)F)cc2[C@H](C)N1C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=FPYLBKFNXBOCNV-NEPJUHHUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 1 (Homo sapiens (Human))	BDBM50355805 (CHEMBL1911750) Show SMILES C[C@@H]1COc2ccc(OC(F)F)cc2[C@H](C)N1C(=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H18ClF2NO3/c1-11-10-25-17-8-7-15(26-19(21)22)9-16(17)12(2)23(11)18(24)13-3-5-14(20)6-4-13/h3-9,11-12,19H,10H2,1-2H3/t11-,12+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Curated by ChEMBL					Assay Description Antagonist activity at OX1R intracellular calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 21: 6414-6 (2011) Article DOI: 10.1016/j.bmcl.2011.08.093 BindingDB Entry DOI: 10.7270/Q2BZ66DH
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50355805 (CHEMBL1911750) Show SMILES C[C@@H]1COc2ccc(OC(F)F)cc2[C@H](C)N1C(=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H18ClF2NO3/c1-11-10-25-17-8-7-15(26-19(21)22)9-16(17)12(2)23(11)18(24)13-3-5-14(20)6-4-13/h3-9,11-12,19H,10H2,1-2H3/t11-,12+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Curated by ChEMBL					Assay Description Antagonist activity at human OX2R expressed in CHO cells assessed intracellular calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 21: 6414-6 (2011) Article DOI: 10.1016/j.bmcl.2011.08.093 BindingDB Entry DOI: 10.7270/Q2BZ66DH
					More data for this Ligand-Target Pair