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SMILES: Cc1ccc2c(N)noc2c1-c1ccc2c(NC(=O)C2(C)C)c1

InChI Key: InChIKey=ARCQYDATEHIVDM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50356005   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50356005
PNG
(CHEMBL1911340)
Show SMILES Cc1ccc2c(N)noc2c1-c1ccc2c(NC(=O)C2(C)C)c1
Show InChI InChI=1S/C18H17N3O2/c1-9-4-6-11-15(23-21-16(11)19)14(9)10-5-7-12-13(8-10)20-17(22)18(12,2)3/h4-8H,1-3H3,(H2,19,21)(H,20,22)
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Article
PubMed
n/an/a 38n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assay

Bioorg Med Chem Lett 21: 6253-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.006
BindingDB Entry DOI: 10.7270/Q25B02W3
More data for this
Ligand-Target Pair