BDBM50356450 CHEMBL1911696

SMILES: O=c1[nH]c(SCC2CCC2)c2CCCCc2c1C#N

InChI Key: InChIKey=GJJPSWNSAXLRSW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50356450 (CHEMBL1911696) Show SMILES O=c1[nH]c(SCC2CCC2)c2CCCCc2c1C#N Show InChI InChI=1S/C15H18N2OS/c16-8-13-11-6-1-2-7-12(11)15(17-14(13)18)19-9-10-4-3-5-10/h10H,1-7,9H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 21: 6693-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.058 BindingDB Entry DOI: 10.7270/Q2FN16M4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50356450 (CHEMBL1911696) Show SMILES O=c1[nH]c(SCC2CCC2)c2CCCCc2c1C#N Show InChI InChI=1S/C15H18N2OS/c16-8-13-11-6-1-2-7-12(11)15(17-14(13)18)19-9-10-4-3-5-10/h10H,1-7,9H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation plate reader				Bioorg Med Chem Lett 21: 6693-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.058 BindingDB Entry DOI: 10.7270/Q2FN16M4
					More data for this Ligand-Target Pair