BDBM50357001 CHEMBL1916428

SMILES: FC(F)(F)S(=O)(=O)Oc1c(c(-c2ccccc2)n2ccc(cc12)C#N)-c1ccccc1

InChI Key: InChIKey=ISUQMUJWDCSSRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM50357001 (CHEMBL1916428) Show SMILES FC(F)(F)S(=O)(=O)Oc1c(c(-c2ccccc2)n2ccc(cc12)C#N)-c1ccccc1 Show InChI InChI=1S/C22H13F3N2O3S/c23-22(24,25)31(28,29)30-21-18-13-15(14-26)11-12-27(18)20(17-9-5-2-6-10-17)19(21)16-7-3-1-4-8-16/h1-13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Botswana Curated by ChEMBL					Assay Description Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenase				Eur J Med Chem 46: 5237-57 (2011) Article DOI: 10.1016/j.ejmech.2011.08.042 BindingDB Entry DOI: 10.7270/Q2ZG6SNF
					More data for this Ligand-Target Pair