BDBM50357002 CHEMBL1916429

SMILES: Cc1ccc(cc1)S(=O)(=O)Oc1c(c(-c2ccccc2)n2ccc(cc12)C#N)-c1ccccc1

InChI Key: InChIKey=PGPNMPWIVVEISH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM50357002 (CHEMBL1916429) Show SMILES Cc1ccc(cc1)S(=O)(=O)Oc1c(c(-c2ccccc2)n2ccc(cc12)C#N)-c1ccccc1 Show InChI InChI=1S/C28H20N2O3S/c1-20-12-14-24(15-13-20)34(31,32)33-28-25-18-21(19-29)16-17-30(25)27(23-10-6-3-7-11-23)26(28)22-8-4-2-5-9-22/h2-18H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Botswana Curated by ChEMBL					Assay Description Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenase				Eur J Med Chem 46: 5237-57 (2011) Article DOI: 10.1016/j.ejmech.2011.08.042 BindingDB Entry DOI: 10.7270/Q2ZG6SNF
					More data for this Ligand-Target Pair