BDBM50357015 CHEMBL1916418

SMILES: COc1c(c(-c2ccccc2)n2ccc(cc12)C#N)-c1ccccc1

InChI Key: InChIKey=BDOYDXBKCMEGLZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM50357015 (CHEMBL1916418) Show SMILES COc1c(c(-c2ccccc2)n2ccc(cc12)C#N)-c1ccccc1 Show InChI InChI=1S/C22H16N2O/c1-25-22-19-14-16(15-23)12-13-24(19)21(18-10-6-3-7-11-18)20(22)17-8-4-2-5-9-17/h2-14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Botswana Curated by ChEMBL					Assay Description Inhibition of rabbit reticulocytes arachidonate 15-lipoxygenase				Eur J Med Chem 46: 5237-57 (2011) Article DOI: 10.1016/j.ejmech.2011.08.042 BindingDB Entry DOI: 10.7270/Q2ZG6SNF
					More data for this Ligand-Target Pair