BDBM50357190 CHEMBL1914590

SMILES: CCCCCCCCCCCc1c(sc2c(Br)csc12)C(O)=O

InChI Key: InChIKey=QPPRWJDMLFTECO-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50357190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50357190 (CHEMBL1914590) Show SMILES CCCCCCCCCCCc1c(sc2c(Br)csc12)C(O)=O Show InChI InChI=1S/C18H25BrO2S2/c1-2-3-4-5-6-7-8-9-10-11-13-15-17(14(19)12-22-15)23-16(13)18(20)21/h12H,2-11H2,1H3,(H,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Corning Inc. Curated by ChEMBL					Assay Description Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution as...				J Med Chem 54: 7385-96 (2011) Article DOI: 10.1021/jm200999f BindingDB Entry DOI: 10.7270/Q2XG9RKZ
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50357190 (CHEMBL1914590) Show SMILES CCCCCCCCCCCc1c(sc2c(Br)csc12)C(O)=O Show InChI InChI=1S/C18H25BrO2S2/c1-2-3-4-5-6-7-8-9-10-11-13-15-17(14(19)12-22-15)23-16(13)18(20)21/h12H,2-11H2,1H3,(H,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a
Corning Inc. Curated by ChEMBL					Assay Description Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcrip...				J Med Chem 54: 7385-96 (2011) Article DOI: 10.1021/jm200999f BindingDB Entry DOI: 10.7270/Q2XG9RKZ
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Homo sapiens (Human))	BDBM50357190 (CHEMBL1914590) Show SMILES CCCCCCCCCCCc1c(sc2c(Br)csc12)C(O)=O Show InChI InChI=1S/C18H25BrO2S2/c1-2-3-4-5-6-7-8-9-10-11-13-15-17(14(19)12-22-15)23-16(13)18(20)21/h12H,2-11H2,1H3,(H,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a
Corning Inc. Curated by ChEMBL					Assay Description Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay				J Med Chem 54: 7385-96 (2011) Article DOI: 10.1021/jm200999f BindingDB Entry DOI: 10.7270/Q2XG9RKZ
					More data for this Ligand-Target Pair