BDBM50357592 CHEMBL1915443

SMILES: Cc1ccccc1Nc1nc2c(cccc2c2cnccc12)-c1nnc[nH]1

InChI Key: InChIKey=YZAAXAWPNUWNKE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50357592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50357592 (CHEMBL1915443) Show SMILES Cc1ccccc1Nc1nc2c(cccc2c2cnccc12)-c1nnc[nH]1 Show InChI InChI=1S/C21H16N6/c1-13-5-2-3-8-18(13)25-21-15-9-10-22-11-17(15)14-6-4-7-16(19(14)26-21)20-23-12-24-27-20/h2-12H,1H3,(H,25,26)(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]				Bioorg Med Chem Lett 21: 6687-92 (2011) Article DOI: 10.1016/j.bmcl.2011.09.059 BindingDB Entry DOI: 10.7270/Q2PR7WD6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50357592 (CHEMBL1915443) Show SMILES Cc1ccccc1Nc1nc2c(cccc2c2cnccc12)-c1nnc[nH]1 Show InChI InChI=1S/C21H16N6/c1-13-5-2-3-8-18(13)25-21-15-9-10-22-11-17(15)14-6-4-7-16(19(14)26-21)20-23-12-24-27-20/h2-12H,1H3,(H,25,26)(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Zarqa University Curated by ChEMBL					Assay Description Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysis				Bioorg Med Chem 25: 4855-4875 (2017) Article DOI: 10.1016/j.bmc.2017.07.036 BindingDB Entry DOI: 10.7270/Q2BC420V
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50357592 (CHEMBL1915443) Show SMILES Cc1ccccc1Nc1nc2c(cccc2c2cnccc12)-c1nnc[nH]1 Show InChI InChI=1S/C21H16N6/c1-13-5-2-3-8-18(13)25-21-15-9-10-22-11-17(15)14-6-4-7-16(19(14)26-21)20-23-12-24-27-20/h2-12H,1H3,(H,25,26)(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]				Bioorg Med Chem Lett 21: 6687-92 (2011) Article DOI: 10.1016/j.bmcl.2011.09.059 BindingDB Entry DOI: 10.7270/Q2PR7WD6
					More data for this Ligand-Target Pair