BDBM50358114 CHEMBL1915936
SMILES: CN(Cc1cccc(O)c1)C(=O)c1ccc(cc1)-c1cccc(O)c1
InChI Key: InChIKey=IHHBRIDBJDPDRX-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) (Homo sapiens (Human)) | BDBM50358114 (CHEMBL1915936) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University Curated by ChEMBL | Assay Description Inhibition of human placental 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 mins by radio flow detector-based HPLC analysis in presenc... | Eur J Med Chem 46: 5978-90 (2011) Article DOI: 10.1016/j.ejmech.2011.10.010 BindingDB Entry DOI: 10.7270/Q2PN9625 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol 17-beta-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50358114 (CHEMBL1915936) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 594 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University Curated by ChEMBL | Assay Description Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabeled, [2,4,6,7-3H]-estradiol as substrate after 20 mins by HPLC analysis in p... | Eur J Med Chem 69: 201-15 (2013) Article DOI: 10.1016/j.ejmech.2013.08.026 BindingDB Entry DOI: 10.7270/Q2639R58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) (Homo sapiens (Human)) | BDBM50358114 (CHEMBL1915936) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University Curated by ChEMBL | Assay Description Inhibition of human placenta 17beta-HSD1 cytosolic fraction using unlabeled, [2,4,6,7-3H]-estrone as substrate after 20 mins by HPLC analysis in pres... | Eur J Med Chem 69: 201-15 (2013) Article DOI: 10.1016/j.ejmech.2013.08.026 BindingDB Entry DOI: 10.7270/Q2639R58 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estradiol 17-beta-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50358114 (CHEMBL1915936) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 594 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University Curated by ChEMBL | Assay Description Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra... | Eur J Med Chem 46: 5978-90 (2011) Article DOI: 10.1016/j.ejmech.2011.10.010 BindingDB Entry DOI: 10.7270/Q2PN9625 | |||||||||||
More data for this Ligand-Target Pair |