BDBM50358553 CHEMBL1923552

SMILES: CCCCCCCCCCCCCCCCOC(=O)CCSC[C@H](N)C(=O)N[C@@H](CO)C(=O)OC

InChI Key: InChIKey=UTDFZJQNGALVIT-GOTSBHOMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 2 (TLR2) (Homo sapiens (Human))	BDBM50358553 (CHEMBL1923552) Show SMILES CCCCCCCCCCCCCCCCOC(=O)CCSC[C@H](N)C(=O)N[C@@H](CO)C(=O)OC |r| Show InChI InChI=1S/C26H50N2O6S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-34-24(30)17-19-35-21-22(27)25(31)28-23(20-29)26(32)33-2/h22-23,29H,3-21,27H2,1-2H3,(H,28,31)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...				J Med Chem 54: 8148-60 (2011) Article DOI: 10.1021/jm201071e BindingDB Entry DOI: 10.7270/Q2KP82K8
					More data for this Ligand-Target Pair