BDBM50359108 CHEMBL1922807

SMILES: NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)CCc1ccccc1

InChI Key: InChIKey=UVFPQOXJGOMRCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359108 (CHEMBL1922807) Show SMILES NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)CCc1ccccc1 |(9.12,5.93,;10.45,5.15,;11.79,5.92,;10.45,3.61,;9.11,2.85,;9.11,1.31,;7.77,.54,;7.77,-.99,;9.1,-1.77,;10.44,-1,;10.44,.55,;9.09,-3.31,;7.85,-4.22,;8.33,-5.68,;9.87,-5.67,;10.89,-6.81,;12.4,-6.49,;12.87,-5.02,;11.84,-3.88,;10.34,-4.21,;11.78,2.84,;11.77,1.3,;13.09,.52,;14.43,1.28,;14.44,2.82,;13.11,3.61,;15.76,.5,;15.75,-1.04,;17.1,1.27,;18.43,.49,;19.77,1.25,;21.09,.46,;22.43,1.22,;22.44,2.76,;21.1,3.54,;19.77,2.78,)| Show InChI InChI=1S/C30H38N4O2/c31-30(36)29(23-16-18-34(19-17-23)28(35)15-10-21-6-2-1-3-7-21)33-24-13-11-22(12-14-24)26-20-32-27-9-5-4-8-25(26)27/h1-9,20,22-24,29,32-33H,10-19H2,(H2,31,36)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human CCR2				Bioorg Med Chem Lett 21: 7496-501 (2011) Article DOI: 10.1016/j.bmcl.2011.09.113 BindingDB Entry DOI: 10.7270/Q22J6C9M
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