BDBM50359112 CHEMBL1922803

SMILES: NC(=O)C(NC1Cc2ccccc2C1)C1CCN(CC1)C(=O)\C=C\c1cc(F)c(F)c(F)c1

InChI Key: InChIKey=HRPOQPDBCIAAKU-AATRIKPKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359112 (CHEMBL1922803) Show SMILES NC(=O)C(NC1Cc2ccccc2C1)C1CCN(CC1)C(=O)\C=C\c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C25H26F3N3O2/c26-20-11-15(12-21(27)23(20)28)5-6-22(32)31-9-7-16(8-10-31)24(25(29)33)30-19-13-17-3-1-2-4-18(17)14-19/h1-6,11-12,16,19,24,30H,7-10,13-14H2,(H2,29,33)/b6-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human CCR2				Bioorg Med Chem Lett 21: 7496-501 (2011) Article DOI: 10.1016/j.bmcl.2011.09.113 BindingDB Entry DOI: 10.7270/Q22J6C9M
					More data for this Ligand-Target Pair