BDBM50359114 CHEMBL1921811

SMILES: NC(=O)C(NC1CCP(=O)(CC1)c1ccccc1)C1CCN(CC1)C(=O)\C=C\c1cc(F)c(F)c(F)c1

InChI Key: InChIKey=LDEBIWOXDWVGAS-VOTSOKGWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359114 (CHEMBL1921811) Show SMILES NC(=O)C(NC1CCP(=O)(CC1)c1ccccc1)C1CCN(CC1)C(=O)\C=C\c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C27H31F3N3O3P/c28-22-16-18(17-23(29)25(22)30)6-7-24(34)33-12-8-19(9-13-33)26(27(31)35)32-20-10-14-37(36,15-11-20)21-4-2-1-3-5-21/h1-7,16-17,19-20,26,32H,8-15H2,(H2,31,35)/b7-6+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human CCR2				Bioorg Med Chem Lett 21: 7496-501 (2011) Article DOI: 10.1016/j.bmcl.2011.09.113 BindingDB Entry DOI: 10.7270/Q22J6C9M
					More data for this Ligand-Target Pair