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SMILES: CCc1cc(-c2ccc3OCC(=O)Nc3c2)n(n1)-c1ccc(F)cc1

InChI Key: InChIKey=LPFDCHPWYGBTDH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359659   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))		BDBM50359659
PNG
(CHEMBL1928883)
Show SMILES CCc1cc(-c2ccc3OCC(=O)Nc3c2)n(n1)-c1ccc(F)cc1
Show InChI InChI=1S/C19H16FN3O2/c1-2-14-10-17(23(22-14)15-6-4-13(20)5-7-15)12-3-8-18-16(9-12)21-19(24)11-25-18/h3-10H,2,11H2,1H3,(H,21,24)
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Similars
Article
PubMed
n/an/a 960n/an/an/an/an/an/a



Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting

J Med Chem 54: 8616-31 (2011)


Article DOI: 10.1021/jm2011645
BindingDB Entry DOI: 10.7270/Q21G0MP5
More data for this
Ligand-Target Pair