BDBM50359667 CHEMBL1929033

SMILES: Fc1cccc(c1)-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F

InChI Key: InChIKey=YCIRKPXWAZZTKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359667 (CHEMBL1929033) Show SMILES Fc1cccc(c1)-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C18H11F4N3O2/c19-11-2-1-3-12(7-11)25-14(8-16(24-25)18(20,21)22)10-4-5-15-13(6-10)23-17(26)9-27-15/h1-8H,9H2,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair