BDBM50359668 CHEMBL1929034

SMILES: FC(F)(F)c1cc(-c2ccc3OCC(=O)Nc3c2)n(n1)-c1ccccc1Cl

InChI Key: InChIKey=NMJZIJZDIXPWLL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359668 (CHEMBL1929034) Show SMILES FC(F)(F)c1cc(-c2ccc3OCC(=O)Nc3c2)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C18H11ClF3N3O2/c19-11-3-1-2-4-13(11)25-14(8-16(24-25)18(20,21)22)10-5-6-15-12(7-10)23-17(26)9-27-15/h1-8H,9H2,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair