BDBM50360194 CHEMBL1927634

SMILES: Nc1nc(NC(=O)c2ccccc2)n2nc(nc2n1)-c1ccco1

InChI Key: InChIKey=JLGTWNQIHBNLLS-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50360194 (CHEMBL1927634) Show SMILES Nc1nc(NC(=O)c2ccccc2)n2nc(nc2n1)-c1ccco1 Show InChI InChI=1S/C15H11N7O2/c16-13-19-14-17-11(10-7-4-8-24-10)21-22(14)15(20-13)18-12(23)9-5-2-1-3-6-9/h1-8H,(H3,16,17,18,19,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells by scintillation counting				J Med Chem 54: (2011) Article DOI: 10.1021/jm101349u BindingDB Entry DOI: 10.7270/Q2445MXP
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50360194 (CHEMBL1927634) Show SMILES Nc1nc(NC(=O)c2ccccc2)n2nc(nc2n1)-c1ccco1 Show InChI InChI=1S/C15H11N7O2/c16-13-19-14-17-11(10-7-4-8-24-10)21-22(14)15(20-13)18-12(23)9-5-2-1-3-6-9/h1-8H,(H3,16,17,18,19,20,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Trieste Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cells by scintillation counting				J Med Chem 54: (2011) Article DOI: 10.1021/jm101349u BindingDB Entry DOI: 10.7270/Q2445MXP
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50360194 (CHEMBL1927634) Show SMILES Nc1nc(NC(=O)c2ccccc2)n2nc(nc2n1)-c1ccco1 Show InChI InChI=1S/C15H11N7O2/c16-13-19-14-17-11(10-7-4-8-24-10)21-22(14)15(20-13)18-12(23)9-5-2-1-3-6-9/h1-8H,(H3,16,17,18,19,20,21,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Trieste Curated by ChEMBL					Assay Description Antagonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase act...				J Med Chem 54: (2011) Article DOI: 10.1021/jm101349u BindingDB Entry DOI: 10.7270/Q2445MXP
					More data for this Ligand-Target Pair