BDBM50360422 CHEMBL1934256

SMILES: Fc1ccc2occ(-c3cccc(c3)C(=O)N[C@@H]3CCCc4cc(CN5CCCCC5)ccc34)c(=O)c2c1

InChI Key: InChIKey=DWBZPBPIXVLIMT-GDLZYMKVSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50360422 (CHEMBL1934256) Show SMILES Fc1ccc2occ(-c3cccc(c3)C(=O)N[C@@H]3CCCc4cc(CN5CCCCC5)ccc34)c(=O)c2c1 |r| Show InChI InChI=1S/C32H31FN2O3/c33-25-11-13-30-27(18-25)31(36)28(20-38-30)23-6-4-8-24(17-23)32(37)34-29-9-5-7-22-16-21(10-12-26(22)29)19-35-14-2-1-3-15-35/h4,6,8,10-13,16-18,20,29H,1-3,5,7,9,14-15,19H2,(H,34,37)/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity to human B1 bradykinin receptor				Bioorg Med Chem Lett 22: 619-22 (2011) Article DOI: 10.1016/j.bmcl.2011.10.068 BindingDB Entry DOI: 10.7270/Q25X29CW
					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Oryctolagus cuniculus)	BDBM50360422 (CHEMBL1934256) Show SMILES Fc1ccc2occ(-c3cccc(c3)C(=O)N[C@@H]3CCCc4cc(CN5CCCCC5)ccc34)c(=O)c2c1 |r| Show InChI InChI=1S/C32H31FN2O3/c33-25-11-13-30-27(18-25)31(36)28(20-38-30)23-6-4-8-24(17-23)32(37)34-29-9-5-7-22-16-21(10-12-26(22)29)19-35-14-2-1-3-15-35/h4,6,8,10-13,16-18,20,29H,1-3,5,7,9,14-15,19H2,(H,34,37)/t29-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	393	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rabbit B1 bradykinin receptor expressed in CHO cells				Bioorg Med Chem Lett 22: 619-22 (2011) Article DOI: 10.1016/j.bmcl.2011.10.068 BindingDB Entry DOI: 10.7270/Q25X29CW
					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50360422 (CHEMBL1934256) Show SMILES Fc1ccc2occ(-c3cccc(c3)C(=O)N[C@@H]3CCCc4cc(CN5CCCCC5)ccc34)c(=O)c2c1 |r| Show InChI InChI=1S/C32H31FN2O3/c33-25-11-13-30-27(18-25)31(36)28(20-38-30)23-6-4-8-24(17-23)32(37)34-29-9-5-7-22-16-21(10-12-26(22)29)19-35-14-2-1-3-15-35/h4,6,8,10-13,16-18,20,29H,1-3,5,7,9,14-15,19H2,(H,34,37)/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human B1 bradykinin receptor expressed in CHO cells by aqueorin-based calcium flux assay				Bioorg Med Chem Lett 22: 619-22 (2011) Article DOI: 10.1016/j.bmcl.2011.10.068 BindingDB Entry DOI: 10.7270/Q25X29CW
					More data for this Ligand-Target Pair