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BDBM50360685 CHEMBL1934103

SMILES: CCn1c2ccccc2c2cc(CCN3CCC4(CC3)C=Cc3ccccc43)ccc12

InChI Key: InChIKey=SBLQTPNTLJBYDJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360685   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360685
PNG
(CHEMBL1934103)
Show SMILES CCn1c2ccccc2c2cc(CCN3CCC4(CC3)C=Cc3ccccc43)ccc12 |c:22|
Show InChI InChI=1S/C29H30N2/c1-2-31-27-10-6-4-8-24(27)25-21-22(11-12-28(25)31)14-18-30-19-16-29(17-20-30)15-13-23-7-3-5-9-26(23)29/h3-13,15,21H,2,14,16-20H2,1H3
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Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair