BindingDB logo
myBDB logout

null

SMILES: CCn1c2ccccc2c2cc(CN3CCC4(CC3)C(Cc3ccccc43)NC(C)=O)ccc12

InChI Key: InChIKey=XIAPDIGMKMGOTB-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360701   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360701
PNG
(CHEMBL1934120)
Show SMILES CCn1c2ccccc2c2cc(CN3CCC4(CC3)C(Cc3ccccc43)NC(C)=O)ccc12
Show InChI InChI=1S/C30H33N3O/c1-3-33-27-11-7-5-9-24(27)25-18-22(12-13-28(25)33)20-32-16-14-30(15-17-32)26-10-6-4-8-23(26)19-29(30)31-21(2)34/h4-13,18,29H,3,14-17,19-20H2,1-2H3,(H,31,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair