BDBM50361117 CHEMBL1933794

SMILES: Brc1ccc2-c3c(CCc2c1)[nH]n(-c1ccccn1)c3=O

InChI Key: InChIKey=QUXUMXQNYGTVFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361117 (CHEMBL1933794) Show SMILES Brc1ccc2-c3c(CCc2c1)[nH]n(-c1ccccn1)c3=O Show InChI InChI=1S/C16H12BrN3O/c17-11-5-6-12-10(9-11)4-7-13-15(12)16(21)20(19-13)14-3-1-2-8-18-14/h1-3,5-6,8-9,19H,4,7H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair