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SMILES: O=C1OCc2cc(ccc12)-c1ccc(s1)-c1cnco1

InChI Key: InChIKey=ZZLZQMTZPMJUAW-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361436   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Perforin-1


(Homo sapiens (Human))		BDBM50361436
PNG
(CHEMBL1934400)
Show SMILES O=C1OCc2cc(ccc12)-c1ccc(s1)-c1cnco1
Show InChI InChI=1S/C15H9NO3S/c17-15-11-2-1-9(5-10(11)7-18-15)13-3-4-14(20-13)12-6-16-8-19-12/h1-6,8H,7H2
NCI pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.18E+3n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...

Bioorg Med Chem 20: 1319-36 (2012)


Article DOI: 10.1016/j.bmc.2011.12.011
BindingDB Entry DOI: 10.7270/Q29C6XW9
More data for this
Ligand-Target Pair