BDBM50361660 CHEMBL1940599

SMILES: Oc1ccc2c(c[nH]c2c1)C(=O)C(=O)N1CCC(Cc2ccccc2)CC1

InChI Key: InChIKey=OLQKBYLFIDAZFH-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50361660 (CHEMBL1940599) Show SMILES Oc1ccc2c(c[nH]c2c1)C(=O)C(=O)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H22N2O3/c25-17-6-7-18-19(14-23-20(18)13-17)21(26)22(27)24-10-8-16(9-11-24)12-15-4-2-1-3-5-15/h1-7,13-14,16,23,25H,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Displacement of [3H](+)pentazocine from sigma 1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting				J Med Chem 54: 8702-6 (2011) Article DOI: 10.1021/jm2008002 BindingDB Entry DOI: 10.7270/Q2ZW1MBK
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50361660 (CHEMBL1940599) Show SMILES Oc1ccc2c(c[nH]c2c1)C(=O)C(=O)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H22N2O3/c25-17-6-7-18-19(14-23-20(18)13-17)21(26)22(27)24-10-8-16(9-11-24)12-15-4-2-1-3-5-15/h1-7,13-14,16,23,25H,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from NMDA receptor GluN2B subunit in Wistar rat cerebral cortex after 120 mins				J Med Chem 55: 10532-9 (2012) Article DOI: 10.1021/jm301508d BindingDB Entry DOI: 10.7270/Q2RN3919
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50361660 (CHEMBL1940599) Show SMILES Oc1ccc2c(c[nH]c2c1)C(=O)C(=O)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H22N2O3/c25-17-6-7-18-19(14-23-20(18)13-17)21(26)22(27)24-10-8-16(9-11-24)12-15-4-2-1-3-5-15/h1-7,13-14,16,23,25H,8-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN2B/NMDA in Wistar rat cerebral cortex after 120 mins by scintillation counting				J Med Chem 54: 8702-6 (2011) Article DOI: 10.1021/jm2008002 BindingDB Entry DOI: 10.7270/Q2ZW1MBK
					More data for this Ligand-Target Pair