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SMILES: O=C(N(Cc1ccccc1-c1cccnc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(nc1)C#N

InChI Key: InChIKey=MAVLBZSYPTWIKY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362140   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))		BDBM50362140
PNG
(CHEMBL1940661)
Show SMILES O=C(N(Cc1ccccc1-c1cccnc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(nc1)C#N
Show InChI InChI=1S/C33H28N6O2/c34-20-27-8-7-25(22-37-27)31-13-14-32(41-31)33(40)39(29-11-9-28(10-12-29)38-18-16-35-17-19-38)23-26-4-1-2-6-30(26)24-5-3-15-36-21-24/h1-15,21-22,35H,16-19,23H2
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MMDB

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Article
PubMed
n/an/a 177n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human MK2

Bioorg Med Chem Lett 22: 65-70 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.074
BindingDB Entry DOI: 10.7270/Q2R78FNS
More data for this
Ligand-Target Pair