BDBM50363035 CHEMBL1945968

SMILES: COc1ccc(cc1)-c1noc(n1)C1CCN(CC1)C(=O)CCC(F)(F)F

InChI Key: InChIKey=BIMBNRWHCVXLAH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional repressor EthR (EthR) (Mycobacterium tuberculosis)	BDBM50363035 (CHEMBL1945968) Show SMILES COc1ccc(cc1)-c1noc(n1)C1CCN(CC1)C(=O)CCC(F)(F)F Show InChI InChI=1S/C18H20F3N3O3/c1-26-14-4-2-12(3-5-14)16-22-17(27-23-16)13-7-10-24(11-8-13)15(25)6-9-18(19,20)21/h2-5,13H,6-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Universit£ Lille Nord de France Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis H37Rv EthR in Mycobacterium tuberculosis H37Rv expressing GFP infected mouse in RAW264.7 cells assessed as p...				J Med Chem 55: 68-83 (2012) Article DOI: 10.1021/jm200825u BindingDB Entry DOI: 10.7270/Q2RX9CJW
					More data for this Ligand-Target Pair