BDBM50363257 CHEMBL1944711

SMILES: Fc1ccc2c(CN(c3ccccc3)c3cccc(Cl)c3)cc(=O)[nH]c2c1F

InChI Key: InChIKey=HZEOHDWNTGXJAV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50363257 (CHEMBL1944711) Show SMILES Fc1ccc2c(CN(c3ccccc3)c3cccc(Cl)c3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C22H15ClF2N2O/c23-15-5-4-8-17(12-15)27(16-6-2-1-3-7-16)13-14-11-20(28)26-22-18(14)9-10-19(24)21(22)25/h1-12H,13H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50363257 (CHEMBL1944711) Show SMILES Fc1ccc2c(CN(c3ccccc3)c3cccc(Cl)c3)cc(=O)[nH]c2c1F Show InChI InChI=1S/C22H15ClF2N2O/c23-15-5-4-8-17(12-15)27(16-6-2-1-3-7-16)13-14-11-20(28)26-22-18(14)9-10-19(24)21(22)25/h1-12H,13H2,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Afraxis Curated by ChEMBL					Assay Description Inhibition of human eNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assay				Bioorg Med Chem Lett 22: 1237-41 (2012) Article DOI: 10.1016/j.bmcl.2011.11.073 BindingDB Entry DOI: 10.7270/Q26W9BJ5
					More data for this Ligand-Target Pair