BDBM50364742 CHEMBL1951891

SMILES: CCOC(=O)c1ccc(Nc2cc(C)nc(Nc3ccc(cc3)C(=O)OCC)n2)cc1

InChI Key: InChIKey=XQABJHMTLNZEJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50364742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human))	BDBM50364742 (CHEMBL1951891) Show SMILES CCOC(=O)c1ccc(Nc2cc(C)nc(Nc3ccc(cc3)C(=O)OCC)n2)cc1 Show InChI InChI=1S/C23H24N4O4/c1-4-30-21(28)16-6-10-18(11-7-16)25-20-14-15(3)24-23(27-20)26-19-12-8-17(9-13-19)22(29)31-5-2/h6-14H,4-5H2,1-3H3,(H2,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of recombinant PDK1 using P2925 peptide as substrate by fluorescence polarization assay				Bioorg Med Chem Lett 22: 1629-32 (2012) Article DOI: 10.1016/j.bmcl.2011.12.121 BindingDB Entry DOI: 10.7270/Q29887GC
					More data for this Ligand-Target Pair