BDBM50365370 CHEMBL4170790

SMILES: Cn1cnc(c1)S(=O)(=O)N1CC(Nc2cccc(Cl)c2)C(C1)c1ccccc1F

InChI Key: InChIKey=QRJOWYRVEKGFJV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50365370 (CHEMBL4170790) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CC(Nc2cccc(Cl)c2)C(C1)c1ccccc1F Show InChI InChI=1S/C20H20ClFN4O2S/c1-25-12-20(23-13-25)29(27,28)26-10-17(16-7-2-3-8-18(16)22)19(11-26)24-15-6-4-5-14(21)9-15/h2-9,12-13,17,19,24H,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...				J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K
					More data for this Ligand-Target Pair