null

SMILES: Fc1cc2OCCCCn3cnnc3-c3cccc(NC(=O)c2cc1C#N)n3

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503654 (US11034671, Example 44 | US11168095, Example 74) Show SMILES Fc1cc2OCCCCn3cnnc3-c3cccc(NC(=O)c2cc1C#N)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Table 2: Alternatively, the protein kinase activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Cor...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M68V5
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503654 (US11034671, Example 44 | US11168095, Example 74) Show SMILES Fc1cc2OCCCCn3cnnc3-c3cccc(NC(=O)c2cc1C#N)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair