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BDBM50366254 CHEMBL296504

SMILES: COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OC(C)(C)Oc3c2)OC1=O

InChI Key: InChIKey=WPQAJPSEELZYJU-FQEVSTJZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50366254   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50366254
PNG
(CHEMBL296504)
Show SMILES COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OC(C)(C)Oc3c2)OC1=O
Show InChI InChI=1S/C25H30N2O6/c1-24(2)32-21-9-4-17(14-22(21)33-24)25(29)10-12-26(13-11-25)15-20-16-27(23(28)31-20)18-5-7-19(30-3)8-6-18/h4-9,14,20,29H,10-13,15-16H2,1-3H3/t20-/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
 16n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047

Bioorg Med Chem Lett 2: 165-170 (1992)


Article DOI: 10.1016/S0960-894X(01)80443-1
BindingDB Entry DOI: 10.7270/Q28P610P
More data for this
Ligand-Target Pair