BDBM50366270 CHEMBL47279
SMILES: COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OC4(CCCC4)Oc3c2)OC1=O
InChI Key: InChIKey=XMKGCIJOCUNXEC-QFIPXVFZSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50366270 (CHEMBL47279) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity against the sigma receptor from guinea pig brain using the radioligand [3H]SKF-10047 | Bioorg Med Chem Lett 2: 165-170 (1992) Article DOI: 10.1016/S0960-894X(01)80443-1 BindingDB Entry DOI: 10.7270/Q28P610P | |||||||||||
More data for this Ligand-Target Pair |