BDBM50366431 CHEMBL1794047

SMILES: C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O

InChI Key: InChIKey=FJFHRLOYVRDSRR-QKOIMYGBSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50366431 (CHEMBL1794047) Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50366431 (CHEMBL1794047) Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50366431 (CHEMBL1794047) Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (Homo sapiens (Human))	BDBM50366431 (CHEMBL1794047) Show SMILES C[C@H](O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H35N2O8P/c1-21(33)27(29(35)36)32-28(34)25(17-22-11-5-2-6-12-22)20-41(38,39)26(18-23-13-7-3-8-14-23)31-30(37)40-19-24-15-9-4-10-16-24/h2-16,21,25-27,33H,17-20H2,1H3,(H,31,37)(H,32,34)(H,35,36)(H,38,39)/t21-,25?,26+,27+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
					More data for this Ligand-Target Pair