BDBM50366781 CHEMBL1790100

SMILES: CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)NC

InChI Key: InChIKey=GYZFFPINSQRJFN-RFFIBUQPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50366781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50366781 (CHEMBL1790100) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)NC Show InChI InChI=1S/C28H42N5O13P/c1-5-15(2)24(28(42)29-4)33-26(40)20(11-13-23(37)38)31-25(39)19(10-12-22(35)36)32-27(41)21(30-16(3)34)14-17-6-8-18(9-7-17)46-47(43,44)45/h6-9,15,19-21,24H,5,10-14H2,1-4H3,(H,29,42)(H,30,34)(H,31,39)(H,32,41)(H,33,40)(H,35,36)(H,37,38)(H2,43,44,45)/t15-,19+,20+,21+,24+/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Products Limited Curated by ChEMBL					Assay Description Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)				Bioorg Med Chem Lett 12: 1365-9 (2002) BindingDB Entry DOI: 10.7270/Q20002MH
					More data for this Ligand-Target Pair