BDBM50366930 CHEMBL1794059

SMILES: NS(=O)(=O)c1cccc(c1)N=CC1C(=O)Nc2ccccc12

InChI Key: InChIKey=QDRYDAKIFWXSTA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50366930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/Cyclin A/Cyclin A1 (Homo sapiens (Human))	BDBM50366930 (CHEMBL1794059) Show SMILES NS(=O)(=O)c1cccc(c1)N=CC1C(=O)Nc2ccccc12 |w:10.10| Show InChI InChI=1S/C15H13N3O3S/c16-22(20,21)11-5-3-4-10(8-11)17-9-13-12-6-1-2-7-14(12)18-15(13)19/h1-9,13H,(H,18,19)(H2,16,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Cyclin-dependent kinase 2 cyclin A				Bioorg Med Chem Lett 14: 953-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.002 BindingDB Entry DOI: 10.7270/Q23R0TDF
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50366930 (CHEMBL1794059) Show SMILES NS(=O)(=O)c1cccc(c1)N=CC1C(=O)Nc2ccccc12 |w:10.10| Show InChI InChI=1S/C15H13N3O3S/c16-22(20,21)11-5-3-4-10(8-11)17-9-13-12-6-1-2-7-14(12)18-15(13)19/h1-9,13H,(H,18,19)(H2,16,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of c-Raf1 kinase				Bioorg Med Chem Lett 14: 953-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.002 BindingDB Entry DOI: 10.7270/Q23R0TDF
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50366930 (CHEMBL1794059) Show SMILES NS(=O)(=O)c1cccc(c1)N=CC1C(=O)Nc2ccccc12 |w:10.10| Show InChI InChI=1S/C15H13N3O3S/c16-22(20,21)11-5-3-4-10(8-11)17-9-13-12-6-1-2-7-14(12)18-15(13)19/h1-9,13H,(H,18,19)(H2,16,20,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)				Bioorg Med Chem Lett 14: 953-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.002 BindingDB Entry DOI: 10.7270/Q23R0TDF
					More data for this Ligand-Target Pair