Found 4 hits for monomerid = 50366931 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM50366931
(CHEMBL1794056)Show SMILES O=C1Nc2ccccc2C1C=Nc1ccc(cc1)-n1cncn1 |w:10.11| Show InChI InChI=1S/C17H13N5O/c23-17-15(14-3-1-2-4-16(14)21-17)9-19-12-5-7-13(8-6-12)22-11-18-10-20-22/h1-11,15H,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of c-Raf1 kinase |
Bioorg Med Chem Lett 14: 953-7 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.002 BindingDB Entry DOI: 10.7270/Q23R0TDF |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50366931
(CHEMBL1794056)Show SMILES O=C1Nc2ccccc2C1C=Nc1ccc(cc1)-n1cncn1 |w:10.11| Show InChI InChI=1S/C17H13N5O/c23-17-15(14-3-1-2-4-16(14)21-17)9-19-12-5-7-13(8-6-12)22-11-18-10-20-22/h1-11,15H,(H,21,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50366931
(CHEMBL1794056)Show SMILES O=C1Nc2ccccc2C1C=Nc1ccc(cc1)-n1cncn1 |w:10.11| Show InChI InChI=1S/C17H13N5O/c23-17-15(14-3-1-2-4-16(14)21-17)9-19-12-5-7-13(8-6-12)22-11-18-10-20-22/h1-11,15H,(H,21,23) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of Cyclin-dependent kinase 2 cyclin A |
Bioorg Med Chem Lett 14: 953-7 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.002 BindingDB Entry DOI: 10.7270/Q23R0TDF |
More data for this Ligand-Target Pair | |
High affinity nerve growth factor receptor
(Homo sapiens (Human)) | BDBM50366931
(CHEMBL1794056)Show SMILES O=C1Nc2ccccc2C1C=Nc1ccc(cc1)-n1cncn1 |w:10.11| Show InChI InChI=1S/C17H13N5O/c23-17-15(14-3-1-2-4-16(14)21-17)9-19-12-5-7-13(8-6-12)22-11-18-10-20-22/h1-11,15H,(H,21,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor) |
Bioorg Med Chem Lett 14: 953-7 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.002 BindingDB Entry DOI: 10.7270/Q23R0TDF |
More data for this Ligand-Target Pair | |