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SMILES: COc1ccc2cc(C(N)=O)n(-c3cccc(CCC(O)=O)c3)c2c1

InChI Key: InChIKey=SSZCWLNXYVKEKT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50366970   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Group 10 secretory phospholipase A2


(Homo sapiens (Human))		BDBM50366970
PNG
(CHEMBL4160502)
Show SMILES COc1ccc2cc(C(N)=O)n(-c3cccc(CCC(O)=O)c3)c2c1
Show InChI InChI=1S/C19H18N2O4/c1-25-15-7-6-13-10-17(19(20)24)21(16(13)11-15)14-4-2-3-12(9-14)5-8-18(22)23/h2-4,6-7,9-11H,5,8H2,1H3,(H2,20,24)(H,22,23)
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Article
PubMed
n/an/a 620n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...

ACS Med Chem Lett 9: 594-599 (2018)


Article DOI: 10.1021/acsmedchemlett.7b00505
BindingDB Entry DOI: 10.7270/Q2Z60RMJ
More data for this
Ligand-Target Pair