BDBM50367114 CHEMBL1765165

SMILES: CCCCn1c2ccc(c(OC)c2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=ZDGVFRADHMKOMF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50367114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50367114 (CHEMBL1765165) Show SMILES CCCCn1c2ccc(c(OC)c2c2ccccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H19F6NO3/c1-3-4-11-28-15-10-9-14(19(30,20(22,23)24)21(25,26)27)17(31-2)16(15)12-7-5-6-8-13(12)18(28)29/h5-10,30H,3-4,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair