BDBM50367126 CHEMBL4163497

SMILES: COc1cc(cc2c3ccccc3c(=O)[nH]c12)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=MYXBFAKWYQVTKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50367126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50367126 (CHEMBL4163497) Show SMILES COc1cc(cc2c3ccccc3c(=O)[nH]c12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H11F6NO3/c1-27-12-7-8(15(26,16(18,19)20)17(21,22)23)6-11-9-4-2-3-5-10(9)14(25)24-13(11)12/h2-7,26H,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
					More data for this Ligand-Target Pair