BDBM50367395 CHEMBL1202763

SMILES: CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)N(C)CCCCc1cccnc1

InChI Key: InChIKey=YEMLTIATOQFOCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50367395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50367395 (CHEMBL1202763) Show SMILES CC(C)c1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)N(C)CCCCc1cccnc1 Show InChI InChI=1S/C26H28N4O2/c1-18(2)20-9-11-23-22(15-20)26(32)30-17-21(10-12-24(30)28-23)25(31)29(3)14-5-4-7-19-8-6-13-27-16-19/h6,8-13,15-18H,4-5,7,14H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human platelet thromboxane synthase (TXA2) was determined in human platelets				J Med Chem 30: 185-93 (1987) BindingDB Entry DOI: 10.7270/Q2222VBH
					More data for this Ligand-Target Pair