BDBM50368368 CHEMBL1202941

SMILES: COc1cccc(c1)C1SCC(=O)N1CCCN(C)C

InChI Key: InChIKey=SDZSLWCLYKIAEU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50368368 (CHEMBL1202941) Show SMILES COc1cccc(c1)C1SCC(=O)N1CCCN(C)C Show InChI InChI=1S/C15H22N2O2S/c1-16(2)8-5-9-17-14(18)11-20-15(17)12-6-4-7-13(10-12)19-3/h4,6-7,10,15H,5,8-9,11H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileum				J Med Chem 35: 2910-2 (1992) BindingDB Entry DOI: 10.7270/Q2XK8G4G
					More data for this Ligand-Target Pair