Found 2 hits for monomerid = 50368603 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cholecystokinin receptor
(RAT) | BDBM50368603
(CHEMBL1237153)Show SMILES OCC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 |r,wU:33.41,31.33,35.39,wD:29.32,TLB:27:28:37.33.32:30,THB:34:33:28.36.35:30,34:35:37.33.32:30,(-1.5,-4.52,;-2.98,-4.08,;-3.35,-2.59,;-4.82,-2.15,;-5.94,-3.22,;-5.57,-4.71,;-6.69,-5.78,;-8.17,-5.34,;-8.53,-3.85,;-7.42,-2.78,;-2.23,-1.52,;-3.41,-.53,;-.75,-1.96,;.36,-.89,;-0,.6,;-1.48,1.04,;-2.7,.1,;-3.97,.96,;-3.54,2.44,;-4.35,3.75,;-3.62,5.11,;-2.08,5.15,;-1.27,3.84,;-2,2.49,;1.84,-1.33,;2.95,-.26,;2.59,1.23,;4.43,-.7,;5.54,.37,;6.92,1.06,;8.29,.37,;9.13,1.84,;9.13,3.24,;7.76,3.93,;6.38,3.24,;6.38,1.84,;7.76,1.14,;6.92,2.46,)| Show InChI InChI=1S/C31H37N3O4/c35-18-25(11-19-6-2-1-3-7-19)30(36)33-28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-12-20-10-21(14-22)15-23(29)13-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29? | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Neuroscience Research Center
Curated by ChEMBL
| Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas |
J Med Chem 35: 1472-84 (1992)
BindingDB Entry DOI: 10.7270/Q2H41S3W |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor
(MOUSE) | BDBM50368603
(CHEMBL1237153)Show SMILES OCC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 |r,wU:33.41,31.33,35.39,wD:29.32,TLB:27:28:37.33.32:30,THB:34:33:28.36.35:30,34:35:37.33.32:30,(-1.5,-4.52,;-2.98,-4.08,;-3.35,-2.59,;-4.82,-2.15,;-5.94,-3.22,;-5.57,-4.71,;-6.69,-5.78,;-8.17,-5.34,;-8.53,-3.85,;-7.42,-2.78,;-2.23,-1.52,;-3.41,-.53,;-.75,-1.96,;.36,-.89,;-0,.6,;-1.48,1.04,;-2.7,.1,;-3.97,.96,;-3.54,2.44,;-4.35,3.75,;-3.62,5.11,;-2.08,5.15,;-1.27,3.84,;-2,2.49,;1.84,-1.33,;2.95,-.26,;2.59,1.23,;4.43,-.7,;5.54,.37,;6.92,1.06,;8.29,.37,;9.13,1.84,;9.13,3.24,;7.76,3.93,;6.38,3.24,;6.38,1.84,;7.76,1.14,;6.92,2.46,)| Show InChI InChI=1S/C31H37N3O4/c35-18-25(11-19-6-2-1-3-7-19)30(36)33-28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-12-20-10-21(14-22)15-23(29)13-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29? | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 976 | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Neuroscience Research Center
Curated by ChEMBL
| Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex |
J Med Chem 35: 1472-84 (1992)
BindingDB Entry DOI: 10.7270/Q2H41S3W |
More data for this
Ligand-Target Pair | |
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