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BDBM50368699 CHEMBL4167917

SMILES: Cn1cnc(c1)S(=O)(=O)NCc1ccc2CC[C@@H]([C@H](Cc3ccccc3)c2c1)N1CCC1

InChI Key: InChIKey=LEUBHBGUPVLRLA-RPWUZVMVSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368699   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))		BDBM50368699
PNG
(CHEMBL4167917)
Show SMILES Cn1cnc(c1)S(=O)(=O)NCc1ccc2CC[C@@H]([C@H](Cc3ccccc3)c2c1)N1CCC1 |r|
Show InChI InChI=1S/C25H30N4O2S/c1-28-17-25(26-18-28)32(30,31)27-16-20-8-9-21-10-11-24(29-12-5-13-29)23(22(21)15-20)14-19-6-3-2-4-7-19/h2-4,6-9,15,17-18,23-24,27H,5,10-14,16H2,1H3/t23-,24+/m1/s1
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Similars
Article
PubMed
 3n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG

Curated by ChEMBL


Assay Description
Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry

J Med Chem 61: 7503-7524 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00300
BindingDB Entry DOI: 10.7270/Q2W66P9B
More data for this
Ligand-Target Pair