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BDBM50368704 CHEMBL4167754

SMILES: CCCS(=O)(=O)NC1CN(C1)c1ccc2OC[C@@H]([C@H](Cc3ccccc3)c2c1)N1CCC1

InChI Key: InChIKey=RLOIGGUTTJARPU-VWNXMTODSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368704   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))		BDBM50368704
PNG
(CHEMBL4167754)
Show SMILES CCCS(=O)(=O)NC1CN(C1)c1ccc2OC[C@@H]([C@H](Cc3ccccc3)c2c1)N1CCC1 |r|
Show InChI InChI=1S/C25H33N3O3S/c1-2-13-32(29,30)26-20-16-28(17-20)21-9-10-25-23(15-21)22(14-19-7-4-3-5-8-19)24(18-31-25)27-11-6-12-27/h3-5,7-10,15,20,22,24,26H,2,6,11-14,16-18H2,1H3/t22-,24+/m1/s1
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KEGG

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PC cid
PC sid
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Similars
Article
PubMed
 44n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG

Curated by ChEMBL


Assay Description
Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry

J Med Chem 61: 7503-7524 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00300
BindingDB Entry DOI: 10.7270/Q2W66P9B
More data for this
Ligand-Target Pair