BDBM50368769 CHEMBL4171585

SMILES: N[C@H]1CCc2ccc(OCCNS(=O)(=O)c3ccccc3)cc2[C@H]1Cc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=FZSZZXOYDRGMRZ-DXFYCEEJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50368769 (CHEMBL4171585) Show SMILES N[C@H]1CCc2ccc(OCCNS(=O)(=O)c3ccccc3)cc2[C@H]1Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C39H53N7O13/c1-20(2)15-26(44-38(57)32(22(4)47)46-34(53)25(40)16-23-11-7-5-8-12-23)36(55)43-27(18-30(48)49)35(54)41-21(3)33(52)42-28(19-31(50)51)37(56)45-29(39(58)59)17-24-13-9-6-10-14-24/h5-14,20-22,25-29,32,47H,15-19,40H2,1-4H3,(H,41,54)(H,42,52)(H,43,55)(H,44,57)(H,45,56)(H,46,53)(H,48,49)(H,50,51)(H,58,59)/t21-,22-,25-,26-,27-,28-,29-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL					Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry				J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B
					More data for this Ligand-Target Pair