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BDBM50368783 CHEMBL4165214

SMILES: N[C@H]1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2[C@H]1Cc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=ZHEPPBPVKCEYIQ-OFNKIYASSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368783   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))		BDBM50368783
PNG
(CHEMBL4165214)
Show SMILES N[C@H]1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2[C@H]1Cc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C23H28Cl2N2O3S/c24-21-7-3-16(12-22(21)25)11-20-19-13-18(6-4-17(19)5-8-23(20)26)30-10-9-27-31(28,29)14-15-1-2-15/h3-4,6-7,12-13,15,20,23,27H,1-2,5,8-11,14,26H2/t20-,23+/m1/s1
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PC sid
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Similars
Article
PubMed
 5.70n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG

Curated by ChEMBL


Assay Description
Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry

J Med Chem 61: 7503-7524 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00300
BindingDB Entry DOI: 10.7270/Q2W66P9B
More data for this
Ligand-Target Pair