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SMILES: COc1ccc(cc1)S(=O)(=O)N(CC=CCN(CC(O)=O)S(=O)(=O)c1ccc(OC)cc1)CC(O)=O

InChI Key: InChIKey=RARSDEHOXJSPFK-ARJAWSKDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369472   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear factor erythroid 2-related factor 2


(Homo sapiens (Human))		BDBM50369472
PNG
(CHEMBL4160703)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC=CCN(CC(O)=O)S(=O)(=O)c1ccc(OC)cc1)CC(O)=O
Show InChI InChI=1S/C22H26N2O10S2/c1-33-17-5-9-19(10-6-17)35(29,30)23(15-21(25)26)13-3-4-14-24(16-22(27)28)36(31,32)20-11-7-18(34-2)8-12-20/h3-12H,13-16H2,1-2H3,(H,25,26)(H,27,28)/b4-3-
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...

J Med Chem 61: 8029-8047 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01133
BindingDB Entry DOI: 10.7270/Q2G163CR
More data for this
Ligand-Target Pair